Magnetic Nanoparticles in Nanomedicine

English | 2024 | PDF | 38 MB | 518 Pages

Kai Wu, Jian-Ping Wang, 044321669X, 0443216681, 9780443216695, 978-0443216695, 9780443216688, 978-0443216688, 978-0-443-21668-8, 978-0-443-21669-5, B0D661QND3

Magnetic Nanoparticles in Nanomedicine provides readers with the fundamental theories and principles of magnetic materials, the synthesis and surface functionalization strategies of MNPs, and the standard techniques for characterizing physicochemical properties of MNPs. Other sections review MNP-based therapies such as magnetic hyperthermia therapy, drug/gene delivery, and magnetic neurostimulation and cover MNP-based in vitro and in vivo disease diagnosis, respectively, including techniques such as magnetoresistive (MR), nuclear magnetic resonance (NMR), magnetic particle spectroscopy (MPS) biosensing platforms, magnetic resonance imaging (MRI), and magnetic particle imaging (MPI). Final chapters address biocompatibility and safety issues in applying MNPs to in vivo biomedical applications, including coverage of the toxicity of MNPs to human tissues, the immune responses of the human body to these particles, as well as blood circulation time of MNPs.

• Provides a valuable tool for academics and clinicians, pushing the frontiers of magnetic-based early-stage disease diagnosis and screening
• Clearly explains the synthesis, functionalization, and biocompatibility of magnetic nanoparticles
• Describes micromagnetic simulation, a valuable tool for predicting the properties of magnetic nanomaterials