Therapeutic Drug Monitoring

by Amitava Dasgupta

Therapeutic Drug Monitoring: Newer Drugs and Biomarkers, Second Edition is an updated reference on TDM analytical techniques in diverse clinical settings. This new edition reviews exciting new developments in the area, including seven new chapters covering immunoassay design and applications, combined chromatographic techniques in therapeutic monitoring, drug monitoring in alternative specimens, pharmacogenomics of anticancer drugs, pharmacogenomics testing for patient management, selected antifungal agents, pharmacodynamic monitoring, and therapeutic drug monitoring of selected anticoagulants. All remaining chapters in the first edition were thoroughly revised and updated. This book is the ideal reference for clinical pathologists, pharmacologists, and toxicologists involved with TDM. Scientists working in diagnostic companies, developing reagents for monitoring therapeutic drugs will also find relevant information in this book.

• Includes new chapters covering antifungal, anticoagulant, and anticancer drugs monitoring
• Discusses limitations of current immunoassays, new and sophisticated chromatographic techniques, the clinical effectiveness of newer antiretroviral agents, anticonvulsants and antidepressants
• Provides full coverage of pharmacogenomics and personalized medicine, principles of pharmacokinetics and pharmacodynamics, and the application of biomarkers in TDM