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Biomarkers in Drug Discovery and Development

Original price was: د.إ986.00.Current price is: د.إ543.00.

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Description

Pages:
586
Language:
English
Format:
PDF
Size:
8 MB
ISBN-10:
1119187508
ISBN-13:
978-1119187509

2nd Edition

by Ramin Rahbari (Editor), Jonathan Van Niewaal (Editor), Michael R. Bleavins (Editor)

This book continues the legacy of a well-established reference within the pharmaceutical industry – providing perspective, covering recent developments in technologies that have enabled the expanded use of biomarkers, and discussing biomarker characterization and validation and applications throughout drug discovery and development.

• Explains where proper use of biomarkers can substantively impact drug development timelines and costs, enable selection of better compounds and reduce late stage attrition, and facilitate personalized medicine
• Helps readers get a better understanding of biomarkers and how to use them, for example which are accepted by regulators and which still non-validated and exploratory
• Updates developments in genomic sequencing, and application of large data sets into pre-clinical and clinical testing; and adds new material on data mining, economics, and decision making, personal genetic tools, and wearable monitoring
• Includes case studies of biomarkers that have helped and hindered decision making
• Reviews of the first edition: “If you are interested in biomarkers, and it is difficult to imagine anyone reading this who wouldn’t be, then this book is for you.” (ISSX) and “…provides a good introduction for those new to the area, and yet it can also serve as a detailed reference manual for those practically involved in biomarker implementation.” (ChemMedChem)

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