Applications of Microdialysis in Pharmaceutical Science

د.إ870.00

Colour Matt Finshed

Description

Year:2011
Pages:576
Language:English
Format:PDF
Size:14 MB
ISBN-10:470409282
ISBN-13:978-0470409282
ASIN:B00BG3EC6I

1st Edition

by Tung-Hu Tsai (Editor)

Discover new and emerging applications for microdialysis in drug evaluation

Microdialysis is a highly valuable sampling tool that can be used in vivo to measure free, unbound analyte concentrations located in interstitial and extracellular spaces. This book explores the full range of clinical applications for microdialysis, focusing on its use in different organ and tissue systems for pharmacokinetic and pharmacodynamic studies. Readers gain a full understanding of the underlying science of microdialysis, current techniques and practices, as well as its many applications in pharmaceutical research.

Applications of Microdialysis in Pharmaceutical Science starts with an introduction to basic principles and then covers analytical considerations, pharmacodynamic and pharmacokinetic studies, clinical aspects, and special applications. Topics include:

  • Role of microdialysis in drug development, including crucial sampling considerations and applications for nervous system diseases
  • Continuous measurement of glucose concentrations in diabetics
  • Applications for clinical evaluation and basic research on organ systems, including monitoring exogenous and endogenous compounds in the lungs
  • Pharmacokinetic and pharmacodynamic evaluation of anticancer drugs
  • Comparison of microdialysis with imaging approaches to evaluate in vivo drug distribution
  • Special applications of microdialysis in studies of cell culture assays, drug-drug interactions, and environmental monitoring

Throughout the book, readers will find simple models that clarify complex concepts and easy-to-follow examples that guide them through key applications in pharmaceutical research. In short, this book enables pharmaceutical researchers to take full advantage of microdialysis techniques for the preclinical and clinical evaluation of drugs and much more.

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.

30
    30
    Your Cart
    Genetic Disease Discovery and Therapeutics
    1 X د.إ1,070.00 = د.إ1,070.00
    Common Pediatric Knee Injuries
    1 X د.إ654.00 = د.إ654.00
    The Kidney of the Critically Ill Pregnant Woman
    1 X د.إ1,029.00 = د.إ1,029.00
    Dear Alzheimers A Diary of Living with Dementia
    1 X د.إ100.00 = د.إ100.00
    Another Persons Poison A History of Food Allergy
    1 X د.إ100.00 = د.إ100.00
    Particle Therapy Technology for Safe Treatment
    1 X د.إ478.00 = د.إ478.00
    IE Basic & Clinical Biostatistics 5th Edition
    1 X د.إ200.00 = د.إ200.00
    Educational Audiology Handbook 3rd Edition
    1 X د.إ280.00 = د.إ280.00
    Ace Education Chemistry O level
    1 X د.إ433.00 = د.إ433.00
    Epidemiology 101 2nd Edition
    1 X د.إ200.00 = د.إ200.00
    General Science & Technology
    1 X د.إ29.00 = د.إ29.00
    Food Allergy By John M James
    1 X د.إ100.00 = د.إ100.00
    Epigenetics in Allergy and Autoimmunity
    1 X د.إ125.00 = د.إ125.00
    Innovative Ultrasound Imaging Techniques
    1 X د.إ612.00 = د.إ612.00
    Extemporaneous Ophthalmic Preparations
    1 X د.إ456.00 = د.إ456.00
    Treatment of Non-infectious Uveitis
    1 X د.إ765.00 = د.إ765.00
    Art of Landscape Photography
    1 X د.إ101.00 = د.إ101.00
    Practical Genitourinary Pathology
    1 X د.إ646.00 = د.إ646.00

    Add to cart